Izumi Uchiha is the wife of Itachi Uchiha.
Uchiha Clan Downfall
Itachi told Izumi to run away because he was going to kill the Uchiha so that the village doesn't get destroyed by the Uchiha, so she did.
Izumi awakened her Sharingan when the Nine-tails attacked the village and her father died. During the Uchiha Clan Downfall, she asked to help Itachi but he said that Mascara might kill her thinking that you aren't gonna help.
During the Chunin Exams, she passed it and became Chunin.